Clinical references, dosing reviews, and literature reviews supporting the Protocol recommendations.
A randomized, double-blind, placebo-controlled trial evaluating the efficacy of daily 200mcg MK-7 supplementation on cortical bone union and structural callus density in patients recovering from extremity fractures.
A pooled analysis of 38 randomized controlled trials identifying threshold limits and dose-response patterns for combining high-dose EPA and DHA to optimize C-reactive protein (CRP) and interleukin-6 levels.
An evaluation of pre-bed timing windows (30, 60, 90 minutes) for magnesium glycinate ingestion and its correlation with N3 deep sleep duration and sleep onset latency markers.
A randomized trial demonstrating that 15g of collagen peptides combined with 50mg of Vitamin C taken 40-60 minutes before loading increases PINP markers of tendon synthesis by 67% compared to post-exercise dosing.